Ziauddin University

🧬 What is the Mega-ROX study?

Mega-ROX is a large international study helping doctors learn the most suitable approach to oxygen therapy that is required for very sick patients who need a ventilator (a machine that helps them breathe in the Intensive Care Unit – ICU).

Oxygen is essential for life, but how much oxygen a patient needs or receives is highly debated among experts. As a result, patients may receive more oxygen than what they need. Some studies say that this is harmful while others say that it is beneficial. So, Mega-ROX aims to find an answer to these queries and help doctors understand the best amount to give so patients can recover comfortably and safely.

🔍 What happens in the study?

  • Patients included in the study are divided into two groups:
    1. One group receives a higher level of oxygen
    2. The other group receives a lower level of oxygen
  • Both groups receive safe and closely monitored care.
  • Doctors carefully check how patients are doing during and after treatment to see which approach supports recovery better.

🌍 Mega-ROX at Ziauddin University

Ziauddin University is part of this important global study which has been reviewed and approved by the National Bioethics Committee of Pakistan.
Our expert team is caring for patients while also contributing to world-class research.
This will help improve patient care in Pakistan and around the world.

📌 Important information for potential participants and their families

  • You or your loved one will be invited to participate in the Mega-ROX study only if the treating doctor feels both types of oxygen treatments are safe and suitable.
  • Taking part in the study is completely your or your family’s choice. You and/or your family can decide together what feels right for you.
  • No matter what you decide, you or your loved one will continue to get the same care and attention from the doctors and nurses.

💡 Why this matters?

This study is helping doctors give oxygen in the most effective and safe way possible. By taking part, patients are helping improve care for themselves and others—now and in the future.

Mega-ROX (Urdu with English subtitles)

Mega-ROX (Pashto)

What is Mega-ROX? (Pashto)

What is Mega-ROX? (Urdu)

Name: Prof Madiha Hashmi
Designation: Principal Investigator
Email: [email protected].pk
Contact No: 021 35862937, Ext. 4460